The dual nature of pilocarpine to stimulate or inhibit the formation of aqueous humor.
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چکیده
منابع مشابه
Influence of intraocular pressure and some drugs on aqueous flow and entry of cycloleucine into the aqueous humor of vervet monkeys (cercopithecus ethiops).
The entry of H-cycloleucine from blood into the anterior chamber and the rate of aqueous humor formation were studied in vervet monkeys. H-cycloleucine was given parenterally. The anterior chamber teas perfused with a buffer solution containing l-albumin or Cinulin. The rate of aqueous humor formation was calculated from the dilution. The rate of entry of H-cycloleucine was estimated from the c...
متن کاملThe effects of pilocarpine on the dynamics of aqueous humor in a primate (Macaca irus)
Albumin labelled with '•"/ and I was used to determine at the same time and. in both eyes the rates of conventional and uveoscleral bulk drainage of aqueous humor in cynomolgus monkeys under pentobarbital anesthesia. With 10'* M per liter of pilocarpine in the anterior chamber, the rate of conventional bulk drainage of aqueous humor was 0.98 ± 0.19 nl per minute as compared with 0.56 ± 0.12 fil...
متن کاملAqueous humor pilocarpine and timolol levels after instillation of the single drug or in combination.
Aqueous humor levels of pilocarpine and timolol in rabbits after administration of either 2% pilocarpine or 0.5% timolol in single-drug solutions were compared with the concentrations found after instillation of a fixed combination of 0.5% timolol and 2% pilocarpine drops. Time intervals considered were 15 min, 30 min, 1 hr, 4 hr, and 8 hr after application. Drug concentrations were analyzed in...
متن کاملNoninvasive assessment of aqueous humor turnover in the mouse eye.
PURPOSE To develop a noninvasive test for monitoring changes in aqueous humor turnover in the mouse eye. METHODS After topical instillation of fluorescein, the rate of decay of fluorescence from aqueous humor and cornea was monitored in Black Swiss, C57 Bl6, and DBA 2J mice with a microscope equipped with epifluorescence and a charge-coupled device (CCD) camera. RESULTS The rate of decay of...
متن کاملStudies of aqueous humor dynamics in man. IV. Effects of pilocarpine upon measurements in young normal volunteers.
The acute effects of topical pilocarpine 4 per cent, administered to one eye, have been studied in replicate experiments in young volunteers. One hour after medication administration the intraocular pressure was significantly lower. The magnitude of the reduction exceeded that predicated from the significant increase of true facility of outflow. This is explained by the observation of a signifi...
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عنوان ژورنال:
- Investigative ophthalmology
دوره 13 8 شماره
صفحات -
تاریخ انتشار 1974